Prepare the connection to the vCenter
Before you can use PowerCLI you have to configure the behavior of PowerCLI if the vCenter provides an unknown certificate. Under normal circumstances – when I am in a separated and firewalled environment, I configure PowerCLI to ignore unknown certificates.
Set-PowerCLIConfiguration -InvalidCertificateAction Ignore
https://vdc-repo.vmware.com/vmwb-repository/dcr-public/847b8d79-9752-43d3-8217-8270ab647679/9e3681cf-989d-4bf9-94b2-30dd819f9abc/GUID-875C2A87-0AC9-4B28-9361-5B283AFE114E.html You need to do this only the first time you use PowerCLI on a system!
A confirmation screen appears, select "Yes to All"
Probably there is a message shown that you should join the VMware Customer Experience Improvement Program.

You can deactivate this with the following command
Set-PowerCLIConfiguration -Scope User -ParticipateInCEIP $false
A confirmation screen appears, select "Yes to All"
Set the option to connect to multiple vcenter at the same time
Set-PowerCLIConfiguration -DefaultVIServerMode Multiple
A confirmation screen appears, select "Yes to All"
After this you can connect to the vCenter
Connect-VIServer -Server <IP or DNS name of the vCenter> `
-Protocol https -User '<username>' -Password '<password>'
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